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2026-11-05
2026-11-06
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5-star Hotels in Panama City

Dreams Playa Bonita All Inclusive

Km 7, Road To Veracruz, Playa Bonita, Panama City, Panama Show map

Dreams Playa Bonita All Inclusive Panama City hotel is situated in a colonial district, 6 km from the class museum "Biomuseo", and boasts a nightclub, karaoke, and playground. The resort is a 15… More

From US$ 275 Book Now

Riu Plaza Panama

Calle 50 Con 53 Este - Urb. Marbella, Panama City, Panama Show map

Offering a convenience store and a restaurant, the 5-star luxurious Riu Plaza Panama Hotel is in the centre of a business neighbourhood, just 6 minutes' walk from the fanciful lifestyle Nina Concept… More

From US$ 107 Book Now

Jw Marriott Panama

Calle Punta Colon, Punta Pacifica, Panama City, Panama Show map

Situated approximately 10 minutes by car from the office F&F Tower, the grand Jw Marriott Panama Hotel features Wi-Fi in public areas, and private parking on site. Offering Caribbean dishes, this 5… More

From US$ 139 Book Now

Gran Evenia Panama Hotel

Calle Eusebio A. Morales Esquina Calle Augusto Samuel Boyd-Urb El Cangrejo, Panama City, Panama Show map

The elegant Gran Evenia Panama Hotel is nestled in the very heart of Panama City, approximately 1 km from Parque Universitario, and features Wi-Fi and secured parking. Located in the Bella Vista… More

From US$ 99 Book Now

Megapolis Hotel Panama

Avenida Balboa Boulevard Elhayek, Panama City, Panama Show map

The luxury Megapolis Hotel Panama, located about a 5-minute walk from Multicentro and 3.3 km from Casco Viejo, features a swimming pool for guests to take a dip in. Offering a fitness studio, the… More

From US$ 113 Book Now

Hotel Bardot Boutique

Calle 1A Oeste, Panama City, Panama Show map

Situated within 5 minutes' walk of Playa El Tuco, the 5-star Hotel Bardot Boutique Panama City offers 13 rooms. Boasting a French restaurant, this Panama City hotel is available steps away from the… More

From US$ 134 Book Now

Waldorf Astoria Panama

47Th St. Uruguay Street, Panama City, Panama Show map

The 5-star Waldorf Astoria Panama Hotel offers quick access to Weil Art Gallery, which is just 5 minutes' walk away. Located a mere 400 metres from StarBay Casino, the 38-storey hotel comprises 133… More

From US$ 125 Book Now

American Trade Hotel

Plaza Herrera, Casco Viejo, Panama City, Panama Show map

Boasting a desirable setting in Casco Viejo with numerous government buildings, cathedrals, museums, churches, art galleries to explore as well as plenty of theatres and concerts to check out nearly… More

From US$ 249 Book Now

Sheraton Grand Panama

Via Israel Y Calle 77 San Francisco, Panama City, Panama Show map

Offering a sunbathing terrace, massage therapy, and a shared lounge, the 5-star Sheraton Grand Panama hotel lies in the very heart of a commercial district, about a 15-minute walk from the shopping… More

From US$ 100 Book Now

Bristol Panama, A Registry Collection Hotel

Calle Aquilino De La Guarida, Panama City, Panama Show map

The upscale Bristol Panama, A Registry Collection Hotel is located just a few steps from the financial district of Panama City merely 300 metres from Royal Casino. In the vicinity of Bingo 90, this… More

From US$ 99 Book Now

W Panama

Calle 50 And Aquilino De La Guardia, Panama City, Panama Show map

The 5-star smoke-free W Panama Hotel is nestled in the very heart of Panama City, within 15 minutes' walk of Parque de la Biblioteca y Arquitectura, and features Wi-Fi and parking. Boasting a… More

From US$ 163 Book Now

Hotel Las Americas Golden Tower Panama

Balboa Avenue and 53 Street Marbella, Panama City, Panama Show map

Perched in the very heart of Marbella, which centers on bustling Avenue Balboa, where a cluster of cafes, cocktail lounges and global restaurants offer a glitzy vibe and expansive sea views, merely 1… More

From US$ 84 Book Now

Sofitel Legend Casco Viejo, Panama City

Calle Primera Oeste San Felipe Casco Viejo, Panama City, Panama Show map

Sofitel Legend Casco Viejo, Panama City hotel, located a 25-minute walk from Figali Convention Center, features Wi-Fi in public areas. This hotel lies right around the corner from the non - profit… More

From US$ 326 Book Now

The Westin Panama

La Rotonda Avenue, Costa Del Este, Panama City, Panama Show map

The Westin Panama Hotel is situated in an upscale area of Panama City, 2.8 km from Conjunto Monumental de Panama Viejo and around a 25-minute walk from Museo Panama Viejo. Featuring a rooftop pool… More

From US$ 149 Book Now

Central Hotel Panama Casco Viejo

Casco Antiguo, Avenida Central Calle 5Ta, Panama City, Panama Show map

Located right in the centre of Panama City, the 5-star Central Hotel Panama Casco Viejo offers fast access to Plaza Tomas Herrera, 16 minutes' walk away. While staying just around the corner from the… More

From US$ 155 Book Now

Le Meridien Panama

C Uruguay Y Avenida De Balboa, Panama City, Panama Show map

The 5-star Le Meridien Panama hotel is situated near an entertainment district, just 5 minutes' walk from Hilton and offers massage therapy and a shared lounge. Boasting the location just near… More

From US$ 197 Book Now

Radisson Hotel Panama Canal

Amador Avenue & Van Hook Street, Panama City, Panama Show map

The 5-star Radisson Hotel Panama Canal, situated within a 6-km distance of Causeway Amador City Park, offers a swimming pool as well as a fitness centre. This Panama City hotel is in the Ancon… More

From US$ 78 Book Now

Aloft By Marriott Panama

Via Israel Calle 76, San Francisco, Panama City, Panama Show map

The 5-star Aloft By Marriott Panama Hotel is situated 500 metres from San Francisco de la Caleta Church and features a nightclub and a sun deck. The hotel lies 2.7 km from StarBay Casino, and offers… More

From US$ 76 Book Now

Hyatt Regency Panama City

Calle 52 And Ricardo Arias, Panama City, Panama Show map

Featuring a steam room, a Jacuzzi, and a sauna, the 5-star Hyatt Regency Panama City hotel is about a 20-minute walk from Majestic Casino. International cuisine plus a heated pool are provided in the… More

From US$ 104 Book Now

Intercontinental Miramar Panama By Ihg

Balboa Avenue, Plaza Miramar, Panama City, Panama Show map

Located close to the shopping district of Panama City, the 5-star luxury Intercontinental Miramar Panama By Ihg Hotel offers a sun deck and massage therapy. This Panama City hotel is in a financial… More

From US$ 124 Book Now

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Calle 125 Este, Urbanizacion Llano Bonito, Panama City, Panama Show map

The 5-star The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City is located 2.8 km from Metromall and boasts 18 holes of golf. Featuring 179 rooms with views of the pool, this elegant… More

From US$ 157 Book Now

Hotel El Panama By Faranda Grand, A Member Of Radisson Individuals

Calle Eusebio A. Morales & Via Espana, Edificio 111, Panama City, Panama Show map

Nestled in the very heart of Panama City and within 25 minutes' walk of Gulf of Panama, the 5-star smoke-free Hotel El Panama By Faranda Grand, A Member Of Radisson Individuals features a traditional… More

From US$ 56 Book Now

Global Hotel Panama

Calle 54 Este Y Avenida Samuel Lewis, Obarrio, Panama City, Panama Show map

The 5-star boutique-style Global Hotel Panama is situated only 1.2 km from Balboa Boutiques and features a Jacuzzi and a sundeck. This Panama City hotel is in a residential area, approximately a 10… More

From US$ 85 Book Now

Hotel La Compania Casco Antiguo

Avenida A Y Calle 8, Casco Ant, Panama City, Panama Show map

Offering a nightclub and spa therapy, the 5-star smoke-free Hotel La Compania Casco Antiguo Panama City is nestled in Casco Viejo with numerous government buildings, cathedrals, museums, churches… More

From US$ 572 Book Now

Marinn Place Financial District

Aquilino De La Guardia Y Calle 52, Panama City, Panama Show map

Nestled in a historical area and a mere 13 minutes' stroll from Jardines de La Colina, the elegant 5-star Marinn Place Financial District Panama City hotel invites guests to dine in a Mexican… More

From US$ 65 Book Now

Waymore Hotel Spa & Casino

Avenida Eusebio A. Morales, Panama City, Panama Show map

Waymore Hotel Spa & Casino Panama City offers 183 rooms an 18-minute walk from El Cangrejo. While boasting a location not far from Vía Argentina underground station, this hotel includes an outdoor… More

From US$ 98 Book Now

Renaissance Panama City Hotel

Via Espana & Ricardo Arias Street, Panama City, Panama Show map

With its prime location only a 6-minute walk from Mini Mall El Cangrejo in Obarrio, which is a bustling retail center home to shopping centers like the upscale SOHO Mall, with big-name designer… More

From US$ 64 Book Now

Hotel San Felipe

Ave. Central Entre Calle 8A Y 9A, Panama City, Panama Show map

Featuring Wi-Fi in public areas, the 5-star Hotel San Felipe Panama City sits 20 minutes' walk from Museum of Contemporary Art. Guests will enjoy a buffet breakfast and access to a terrace. More

From US$ 86 Book Now

Hostal Yoha

Av. 5A B. Sur, Panama City, Panama Show map

The 5-star Hostal Yoha Panama City hotel, located just a 5-minute walk from StarBay Casino and 200 metres from Balboa Boutiques, features a year-round outdoor swimming pool for guests to take a dip… More

From US$ 32 Book Now

Sortis Hotel, Spa & Casino, Autograph Collection

Calle 56 Y 57, Obarrio, Panama City, Panama Show map

Sortis Hotel, Spa & Casino, Autograph Collection Panama City offers a nightclub, a sunbathing terrace, and a shared lounge and sits 6 minutes' walk from the fanciful lifestyle Nina Concept Store. More

From US$ 109 Book Now

La Residence Panama

Calle Beatriz M. De Cabal & Calle 50, Panama City, Panama Show map

Located around a 25-minute stroll from Avenida Balboa Waterside Road, the elegant 5-star La Residence Panama hotel offers Wi-Fi in the rooms and a private parking lot. An à la carte restaurant is… More

From US$ 122 Book Now

Villa Palma Small Luxury Hotel

Calle 1A Oeste, Panama City, Panama Show map

The 5-star Villa Palma Small Luxury Hotel Panama City gives quick access to Paseo de Las Bovedas, situated only a 5-minute walk away. This Panama City hotel features safety facilities including a… More

From US$ 220 Book Now

Dovle Branded Residences By Hms - Preferred Member

Dovle Cincuentenario, Panama City, Panama Show map

The 5-star Dovle Branded Residences By Hms - Preferred Member Panama City hotel offers its guests air-conditioned rooms only 5 minutes' walk from Museo Panama Viejo. Situated around 7 km from Casco… More

From US$ 192 Book Now

Eurostars Panama City

Calle Ricardo Arias Bellavista Via Espana, Panama City, Panama Show map

The 5-star Eurostars Panama City hotel, located approximately a 5-minute walk from Iglesia del Carmen and 2.1 km from the exclusive Punta Paitilla, features a rooftop pool for guests to take a dip in… More

From US$ 59 Book Now

Gran Evenia Panama

Eusebio A. Morales Esq, C. Augusto Samuel Boyd,, Panama City, Panama Show map

Located 3.5 km from Camino de Cruces, Gran Evenia Panama Hotel offers air-conditioned rooms around a 25-minute walk from Cinta Costera. A swimming pool and a lounge bar are offered for guest… More

Book Now